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mouse anti human epcam antibody  (Santa Cruz Biotechnology)


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    Santa Cruz Biotechnology mouse anti human epcam antibody
    Mouse Anti Human Epcam Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 95/100, based on 193 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+anti+human+epcam/pmc12901050-414-6-10?v=Santa+Cruz+Biotechnology
    Average 95 stars, based on 193 article reviews
    mouse anti human epcam antibody - by Bioz Stars, 2026-07
    95/100 stars

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    Image Search Results


    GucyCART induces GUCY2C loss in multiple low antigen models. (A) LS174T, SKCO1, and LoVo CRC cells were exposed to GucyCART for 48 hours. (B) Cytolysis kinetics were quantified over the 48 hour co-culture. AUCs were calculated for each condition, and one-way ANOVA was used to compare GucyCART and control CART at each E:T ratio. Each data point in (B) represents the mean ± SD from n ≥ 3 technical replicates in a single experiment that is representative of 3–5 experiments; **** p < 0.0001. (C, D) Following 48 hours of cytolysis, remaining cells were collected, and GUCY2C mRNA (C) and protein (D) were quantified relative to the epithelia-specific housekeeping control EPCAM. Each data point represents the average of biological replicates in separate experiments (N = 3–5 experiments). One-way ANOVA was used to compare each E:T of GucyCART to control CART; ** p < 0.01, *** p < 0.0001. Figure schematics were generated using BioRender.com .

    Journal: Frontiers in Immunology

    Article Title: IFNγ-induced antigen loss in chimeric antigen receptor-T cell therapy

    doi: 10.3389/fimmu.2026.1772472

    Figure Lengend Snippet: GucyCART induces GUCY2C loss in multiple low antigen models. (A) LS174T, SKCO1, and LoVo CRC cells were exposed to GucyCART for 48 hours. (B) Cytolysis kinetics were quantified over the 48 hour co-culture. AUCs were calculated for each condition, and one-way ANOVA was used to compare GucyCART and control CART at each E:T ratio. Each data point in (B) represents the mean ± SD from n ≥ 3 technical replicates in a single experiment that is representative of 3–5 experiments; **** p < 0.0001. (C, D) Following 48 hours of cytolysis, remaining cells were collected, and GUCY2C mRNA (C) and protein (D) were quantified relative to the epithelia-specific housekeeping control EPCAM. Each data point represents the average of biological replicates in separate experiments (N = 3–5 experiments). One-way ANOVA was used to compare each E:T of GucyCART to control CART; ** p < 0.01, *** p < 0.0001. Figure schematics were generated using BioRender.com .

    Article Snippet: Membranes were probed using an anti-human GUCY2C antibody (37517, Cell Signaling Technology), anti-human GAPDH (2118S, Cell Signaling Technology), anti-human STAT1 (14994T, Cell Signaling Technology), anti-human phospho-STAT1 (9167S, Cell Signaling Technology), anti-human CHOP (2895S, Cell Signaling Technology), anti-human β-actin (2128S, Cell Signaling Technology), anti-human EpCAM (2929S, Cell Signaling Technology) anti-human CDH17 (88594T, Cell Signaling Technology), and anti-human HER2 (2165T, Cell Signaling Technology).

    Techniques: Co-Culture Assay, Control, Generated